The New England Patriots might actually face some sort of resistance this week, while the Miami Dolphins could get their first win.
All odds provided by FanSided’s partner, The Action Network.
San Francisco 49ers (-10) at Arizona Cardinals
Thursday night always brings out sloppy games and weird box scores. Still, the 49ers (7-0) should get ample pressure on Kyler Murray and hand the Cardinals (3-4-1) another loss. Just an imbalance in talent here.
Pick: San Francisco 24, Arizona 13
Houston Texans (-2) at Jacksonville Jaguars
This bad boy is in London. You know who plays in London every year? The Jaguars (4-4). You know who doesn’t? The Texans (5-3). That matters. It also matters that Jacksonville’s defensive front is a terrible matchup for Houston, and that J.J. Watt is gone for the season.
Pick: Jacksonville 19, Houston 17
Chicago Bears at Philadelphia Eagles (-5)
The Eagles (4-4) should win this game. They are getting healthier, the Bears (3-4) are a complete mess behind Matt Nagy and Mitchell Trubisky, and the game is at The Link. Philadelphia has a chance to get rolling a bit here.
Pick: Philadelphia 23, Chicago 20
Indianapolis Colts at Pittsburgh Steelers (EVEN)
This game has even odds. That tells you plenty about Vegas’ thoughts on the Colts (5-2). Indianapolis has been a terrific story, but the numbers say this is a below-average team. The Steelers (3-4) are fighting to get back into the mix, and can do so with a victory. Taking them at home.
Pick: Pittsburgh 21, Indianapolis 18